S-4 Physical Pharmaceutics II - Free Notes

Physical Pharmaceutics II Notes (S-4)

Physical Pharmaceutics II Notes

Below are well-organized, unit-wise Physical Pharma II notes available for free.
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Colloidal Dispersion in Physical Pharmaceutics II

Unit 1

Colloidal dispersions

Unit I covers colloidal dispersions, classification of dispersed systems, particle size and shape, and types of colloids. It includes optical, kinetic, electrical properties, and effects of electrolytes, coacervation, peptization, and protective action.

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Unit 2

Rheology & Deformation of solids

Unit II covers rheology of Newtonian and non-Newtonian systems, flow laws, viscosity, temperature effects, and thixotropy in formulations. It also includes solid deformation, stress, strain, elastic modulus, and the Heckel equation.

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Unit 3

Coarse dispersion

Unit III covers coarse dispersions like suspensions and emulsions, interfacial properties, settling, flocculation, deflocculation, emulsification theories, micro/multiple emulsions, stability, preservation, rheology, and HLB-based formulation.

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Unit 4

Micromeritics

Unit IV focuses on micromeritics: particle size, distribution (mean, number, weight), shape, specific surface, and surface area determination. It also covers powder properties like porosity, density, packing, bulkiness, and flow characteristics.

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Unit 5

Drug stability

This Unit covers drug stability and reaction kinetics (zero, pseudo-zero, first, second order), factors affecting degradation (e.g., temperature, solvent), stabilization methods, accelerated stability testing, and photolysis prevention.

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